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Yes
Zolpidem Tartrate
Insomnia
Zolpidem is an imidazopyridine which selectively binds the omega-1 receptor subtype (also known as the benzodiazepine-1 subtype) which is the alpha unit of the GABA-A receptor complex. Whereas benzodiazepines non-selectively bind all three omega receptor subtypes, zolpidem preferentially binds the omega-1 subtype. The modulation of the chloride anion channel via this receptor leads to the specific sedative effects demonstrated by zolpidem. These effects are reversed by the benzodiazepine antagonist flumazenil.
Zolpidem Tartrate
Memory disorders such as poor memory (amnesia), memory impairment, anterograde amnesia , hallucinations ; Drowsiness or a strong desire to sleep ; Dizziness ; Diarrhoea ; Feeling sick (nausea) or being sick (vomiting) ; Abdominal pain ; Infection of the lungs or airways (respiratory infection) ; Headache ; Feeling tired or agitated ; Nightmares ; Depression ; Back pain.
Antipsychotics , sertraline , narcotic analgesics , anticonvulsants , anaesthetics , hypnotics , sedative antihistamines such as chlorphenamine or promethazine , antidepressants including bupropion, desipramine, fluoxetine, sertraline and venlafaxine.
It is used for short-term treatment of insomnia in patients over 18 years of age, that is causing you severe distress or that is affecting your everyday life.
Do not use if you are allergic (hypersensitive) to zolpidem tartrate or any of the other ingredients of this medicine ; As a long-term treatment. Treatment should be as short as possible, because the risk of dependence increases with the duration of treatment ; If you have ever experienced sleep walking or other behaviours which are unusual while sleeping (such as driving, eating, making a phone call or having sex etc.) while not being fully awake after taking zolpidem tartrate tablets or other medicines containing zolpidem .
Concomitant use of zolpidem and opioids may result in sedation, respiratory depression, coma and death. Because of these risks, concomitant prescribing of sedative medicines such as benzodiazepines or related drugs such as zolpidem with opioids should be reserved for patients for whom alternative treatment options are not possible.
Hypnotics such as zolpidem are not recommended for the primary treatment of psychotic illness.
Use of zolpidem may lead to the development of abuse and/or physical and psychological dependence. The risk of dependence increases with dose and duration of treatment. Cases of dependence have been reported more frequently in patients treated with zolpidem for longer than 4 weeks. The risk of abuse and dependence is also greater in patients with a history of psychiatric disorders and/or alcohol, substance or drug abuse. Zolpidem should be used with extreme caution in patients with current or a history of alcohol, substance or drug abuse or dependence.
Due to its pharmacological properties, zolpidem can cause drowsiness and a decreased level of consciousness, which may lead to falls and consequently to severe injuries.
Always consult your physician before using any medicine.
Store this medicine at room temperature, away from direct light and heat.
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