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Specification
Requires Prescription (YES/NO)
Yes
Generics
Fluvoxamine Maleate
Used For
Obsessive Compulsive Disorder
How it works
Fluvoxamine works by stopping the serotonin that has been released from being reabsorbed back into the nerve cells in the brain. This helps to prolong its effects and over time this helps to lighten mood and relieve depression.
Usage And Safety
Dosage
Fluvoxamine Maleate
Side Effects
Headache, nausea, diarrhea, dry mouth, dizziness, increased sweating, feeling nervous, restless, fatigued, or having trouble sleeping (insomnia).
Drug Interactions
Fluvoxamine should not be used in combination with MAOIs including linezolid, due to risk of serotonin syndrome. Fluvoxamine can inhibit the metabolism of drugs metabolized by certain cytochrome P450 isoenzymes.Plasma concentrations of propranolol are increased in combination with fluvoxamine, the propranolol dose may need to be lowered.Plasma concentrations of ropinirol may be increased in combination with fluvoxamine thus increasing the risk of overdose , Warfarin.
Indication
• Major depressive episode. • Obsessive Compulsive Disorder (OCD) .
When not to Use
It is contraindicated in combination with tizanidine and monoamine oxidase inhibitors (MAOIs).
Precautions
Precaution
Suicide/suicidal thoughts or clinical worsening Depression is associated with an increased risk of suicidal thoughts, self harm and suicide (suicide-related events). This risk persists until significant remission occurs. As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored until such improvement occurs.
Warnings
Warning 1
Fluvoxamine should not be used in the treatment of children and adolescents under the age of 18 years except for patients with OCD. Due to lack of clinical experience the use of fluvoxamine in children for the treatment of depression cannot be recommended .
Warning 2
Patients suffering from hepatic or renal insufficiency should start on a low dose and be carefully monitored. Treatment with fluvoxamine has rarely been associated with an increase in hepatic enzymes, generally accompanied by clinical symptoms. In such cases treatment should be discontinued .
Warning 3
Glycaemic control may be disturbed (i.e., hyperglycaemia, hypoglycaemia, decreased glucose tolerance), especially in the early stages of treatment. The dosage of anti-diabetic drugs may need to be adjusted .
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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