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Specification
Requires Prescription (YES/NO)
Yes
Generics
Mebendazole
Used For
Parasitic Infection
How it works
Mebendazole acts locally in the lumen of the gut by interfering with cellular tubulin formation in the intestines of worms. Mebendazole binds specifically to tubulin and causes ultrastructural degenerative changes in the intestine. As a result, the glucose uptake and the digestive functions of the worm are disrupted to such an extent that an autolytic process occurs.
Usage And Safety
Dosage
Mebendazole
Side Effects
Abdominal Discomfort, Diarrhea, Flatulence , Agranulocytosis, Neutropenia , Hypersensitivity including anaphylactic reaction and anaphylactoid reaction , Convulsions, Dizziness , Abdominal pain, Nausea, Vomiting , Hepatitis, Abnormal liver function tests , Toxic epidermal necrolysis, Stevens-Johnson syndrome, Exanthema, Angioedema, Urticaria, Alopecia , Glomerulonephritis.
Drug Interactions
Cimetidine , metronidazole.
Indication
It is used for the treatment of gastrointestinal worm infestations.
When not to Use
Mebendazole is contraindicated in persons with a known hypersensitivity to the drug or its excipients.
Precautions
Precaution
Mebendazole 100 mg should only be given to very young children if their worm infestation interferes significantly with their nutritional status and physical development.
Warnings
Warning 1
There have been rare reports of reversible liver function disturbances, hepatitis, and neutropenia described in patients who were treated with mebendazole at standard dosages for indicated conditions.
Warning 2
As higher doses and longer treatment is recommended in patients with Trichinellosis and Echinoccocosis, careful consideration should be given when treating patients with severe chronic hepatic diseases and/or bone marrow depression.
Warning 3
Mebendazole does not affect the mental alertness or driving ability.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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