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Specification
Requires Prescription (YES/NO)
Yes
Generics
Cephradine
Used For
Bacterial Infection
How it works
Cephradine inhibits the final transpeptidation step of the peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillinbinding proteins (PBPs), thus arresting cell wall synthesis leading to bacterial cell death.
Usage And Safety
Dosage
Cephradine
Side Effects
Gastrointestinal: Glossitis, nausea, vomiting, diarrhea or loose stools, tenesmus, abdominal paincolitis and pseudomembranous colitis. Hypersensitivity: Mild urticaria or skin rash, edema, erythema, pruritis, joint pain and drug fever. Hematologic: Mild, transient eosinophilia, leukpenia and neutropenia. Other: Headache, dizziness, dyspnea, paresthesia, candidal overgrowth and vaginitis.
Drug Interactions
Loop diuretics , probenecid , aminoglycosides , anticoagulants.
Indication
Cephradine is indicated in the treatment of following infections:Upper respiratory tract infections: Sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis and otitis media.Lower respiratory tract infections: Acute and chronic bronchitis, lobar and bronchopneumonia.Skin and soft tissue infections: Impetigo, abscess, cellulitis and furunculosis. Urinary tract infections: Cystitis, urethritis and pyelonephritis.Gastrointestinal tract infections: Bacillary dysentery, enteritis and peritonitis
When not to Use
Cephradine is contraindicated in patients with known hypersensitivity to cephradine or to any excipient of the product.
Precautions
Precaution
Cephradine should be used with caution in patients with known hypersensitivity to penicillins because of partial allergenicity between penicillins and the cephalosporins .
Warnings
Warning 1
Caution should be exercised in patients with renal failure and dosage should be reduced.
Warning 2
False positive reaction for glucose in the urine may occur with Benedict's or Fehling's solution or with reagent tablets such as Clinitest following administration of cephradine.
Warning 3
Prolonged use with antibiotics may result in overgrowth of non susceptible microorganisms.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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