Triplixam Tablets 5Mg/1.25Mg/5Mg (1 Bottle = 30 Tablets)

Requires Prescription (YES/NO)

Yes

Generics

Perindopril Arginine, Indapamide , Amlodipine Besilate

Used For

Hypertension

How it works

Each of the active ingredients reduces blood pressure and they work together to control your blood pressure: - Perindopril belongs to a class of medicines called Angiotensin Converting Enzyme (ACE) inhibitors. It works by widening the blood vessels, which makes it easier for your heart to pump blood through them. - Indapamide is a diuretic (which belongs to a class of medicines called sulfonamide derivatives with an indole ring). Diuretics increase the amount of urine produced by the kidneys. However, indapamide is different from other diuretics, as it only causes a slight increase in the amount of urine produced. - Amlodipine is a calcium channel blockers (which belongs to a class of medicines called dihydropyridines). It works by relaxing blood vessels, so blood passes through easily.

Dosage

Perindopril Arginine, Indapamide , Amlodipine Besilate

Side Effects

Sudden wheeziness, chest pain, shortness of breath, or difficulty in breathing, - swelling of eyelids, face or lips, - swelling of the mouth, tongue and throat, which causes great difficulty breathing, - severe skin reactions including intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (Stevens Johnson Syndrome, Toxic Epidermal Necrolysis) or other allergic reactions, - severe dizziness or fainting, - heart attack, , life-threatening irregular beat.(Not known) - inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell .

Drug Interactions

Lithium (used to treat some mental health disorders such as mania, manic depressive illness and recurrent depression), potassium-sparing drugs (e.g. triamterene, amiloride), potassium supplements or potassium-containing salt substitutes,other drugs which can increase potassium in your body (such as heparin and cotrimoxazole also known as trimethoprim/sulfamethoxazole), dantrolene (infusion) is also used to treat malignant hyperthermia during anaesthesia (symptoms including very high fever and muscle stiffness), estramustine (used in cancer therapy), medicines, which are most often used to treat diarrhea (racecadotril) or avoid rejection of transplanted organs (sirolimus, everolimus, temsirolimus and other drugs belonging to the class of so-called mTor inhibitors)., sacubitril/valsartan (used to treat long-term heart failure). other medicines used to treat high blood pressure: angiotensin-converting-enzyme inhibitor and angiotensin receptor blockers.

Indication

It is an antihypertensive medicine used in the treatment of high blood pressure (hypertension).

When not to Use

Do not take if you are allergic to perindopril or other ACE-inhibitors, indapamide or other sulfonamides, amlodipine or other dihydropyridines, or any of the other ingredients of this medicine .

Precaution

Talk to your doctor or pharmacist or nurse before taking if you have hypertrophic cardiomyopathy (heart muscle disease) or renal artery stenosis (narrowing of the artery supplying the kidney with blood) .

Warning 1

Talk to your doctor or pharmacist or nurse before taking if you are on a salt restricted diet or use salt substitutes which contain potassium (a well-balanced potassium blood level is essential) .

Warning 2

Talk to your doctor or pharmacist or nurse before taking if you are black origin you may have higher incidence of angiodema (swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing) and less effective in lowering blood pressure .

Warning 3

Talk to your doctor or pharmacist or nurse before taking if you have swelling of the face, lips, mouth , tongue or throat which may cause difficulty in swallowing or breathing (angioedema), which can occur at any time during treatment, stop your treatment immediately and directly contact your doctor.

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.