Serloft Tablets 50Mg (1 Strip = 10 Tablets)

Requires Prescription (YES/NO)

Yes

Generics

Sertraline HCl

Used For

Depression

How it works

Sertraline potentiates serotonergic activity in the central nervous system through inhibition of neuronal reuptake of serotonin (5-HT).

Dosage

Sertraline HCl

Side Effects

Hypersensitivity reactions to sertraline , Disulfiram-alcohol reaction when ZOLOFT oral solution is taken with disulfiram , QT prolongation and ventricular arrhythmias when taken with pimozide , Suicidal thoughts and behaviors , Serotonin syndrome , Increased risk of bleeding , Activation of mania/hypomania , Discontinuation syndrome , Seizures , Angle-closure glaucoma , Hyponatremia.

Drug Interactions

Selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue , other SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John’s Wort, aspirin, clopidogrel, heparin, warfarin , propafenone, flecainide, atomoxetine, desipramine, dextromethorphan, metoprolol, nebivolol, perphenazine, thoridazine, tolterodine, venlafaxine , fosphenytoin .

Indication

Sertraline HCl is indicated for the treatment of the following *Major depressive disorder (MDD) * Obsessive-compulsive disorder (OCD) * Panic disorder (PD)

When not to Use

It is contraindicated in patients:-Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome.- Taking pimozide- With known hypersensitivity to sertraline (e.g., anaphylaxis, angioedema).

Precaution

Exposure to SSRIs and SNRIs, including sertraline HCl in late pregnancy may lead to an increased risk for neonatal complications requiring prolonged hospitalization, respiratory support, and tube feeding, and/or persistent pulmonary hypertension of the newborn (PPHN).

Warning 1

Serotonin-norepinephrine reuptake inhibitors (SNRIs) and SSRIs, including sertraline HCl , can precipitate serotonin syndrome, a potentially life-threatening condition .

Warning 2

Drugs that interfere with serotonin reuptake inhibition, including sertraline HCl, increase the risk of bleeding events. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk.

Warning 3

Hyponatremia may occur as a result of treatment with SNRIs and SSRIs, including sertraline HCl. Cases with serum sodium lower than 110 mmol/L have been reported .

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.