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Yes
Silver Sulphadiazine
Topical Antibacterial
Silver sulfadiazine disintegrates in the burn wound, thereby causing a slow and sustained release of silver ions. Silver ions bind to bacterial desoxyribonucleic acid, thus inhibiting the growth and multiplication of bacterial cells without affecting the cells of the skin and subcutaneous tissue.
Silver Sulphadiazine
The following listed side effects occur often: Skin irritation, burning, itching, pain at the site of administration, rash, decreased white blood cell count (white blood cells) in the blood count, gray skin color. Because of the potential reduction in the number of white blood cells, blood count should be regularly monitored during treatment. The following listed side effects occur very rarely: Life-threatening reactions on the skin (Stevens-Johnson syndrome, toxic epidermal necrolysis). The following listed side effects occur at unknown frequency: Hypersensitivity reactions, allergic skin reactions such as rash, itching, dermatitis, which can occur only as a burning sensation or pain at the site of administration or thirst.
Phenytoin, sulphonamides, oral hypoglycaemics, enzymatic debriding agents.
It is used for the prevention and the treatment of inflammation (infection) in burns and other skin injuries.
Do not take • If you are allergic (hypersensitive) to sulfadiazine and / or any other ingredient of this product • During pregnancy (especially in the prenatal period) (see section Pregnancy and breastfeeding) • In preterm infants and newborns during the first 2 months of life, because it may cause jaundice (kernicterus) • This cream contains peanut oil. People who are allergic to peanut oil or soybean should not use this medicine.
The risk of severe skin reactions is highest during the first few weeks of treatment. If you experience skin rash or mentioned symptoms on the skin, please seek immediate medical advice and tell your doctor about using this medicine.
Caution is required in the presence of hypersensitivity to sulfonamides because of possible allergic reactions; in patients with inborn G-6-PD deficiency as hemolysis may occur after the application of the cream to the large body surface area; as well as in the presence of hepatic and renal dysfunction.
When treatment with silver sulphadiazine cream involves prolonged administration or large burn surfaces, the white blood cell count should be monitored, as leukopenia may occur.
As with other local antimicrobials, you may experience superinfection (re-inflammation after treatment of the same person) after treatment with silver sulfadiazine.
Always consult your physician before using any medicine.
Store this medicine at room temperature, away from direct light and heat.
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