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Specification
Requires Prescription (YES/NO)
Yes
Generics
Rabeprazole Sodium
Used For
Acidity & Ulcers
How it works
Rabeprazole belongs to a new class of antisecretory compounds (substituted benzimidazole proton-pump inhibitor) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+ /K+ ATPase at the parietal cell. The effect is dose related and leads to the inhibition of both basal and stimulated acid secretion irrespective to the stimulus.
Usage And Safety
Dosage
Rabeprazole Sodium
Side Effects
Common: Headache, diarrhea and nausea. Other adverse events were rhinitis, abdominal pain, asthenia, flatulence, pharyngitis, vomiting, non-specific pain/back pain, dizziness, flu like syndrome, infection, cough,constipation and insomnia. Less frequent: Rash, myalgia, chest pain, dry mouth, dyspepsia, nervousness, somnolence, bronchitis, sinusitis, chills, eructation, leg cramps, urinary tract infection, arthralgia and fever.Rare: Anorexia, gastritis, weight gain, depression, pruritus, vision or taste disturbances, stomatitis, sweating and leucocytosis, thrombocytopenia, neutropenia and leukopenia.
Drug Interactions
Ketoconazole or itraconazole .
Indication
It is indicated for the treatment of the following: - Active duodenal ulcer - Active benign gastric ulcer - Symptomatic Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD).
When not to Use
Rabeprazole is contraindicated:- In patients with known hypersensitivity to rabeprazole or other substituted benzimidazoles or any component of this product.- In pregnancy and during breast-feeding. Rabeprazole sodium is not recommended for children, as there is no experience of its use in this group.
Precautions
Precaution
The possibility of malignancy should be excluded prior to commencing treatment with rabeprazole as symptomatic response to therapy with rabeprazole sodium does not preclude the presence of gastric or esophageal malignancy. Patients on long-term treatment (particularly those treated for more than a year) should be kept under regular surveillance.
Warnings
Warning 1
Rabeprazole should be used with caution in patients with severe hepatic dysfunction.
Warning 2
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
Warning 3
Proton pump inhibitors (such as rabeprazole) may increase your risk for bone fractures, especially with longer use, higher doses, and in older adults.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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