Progeffik Softgel Capsules 100Mg (1 Strip = 15 Capsules)

Requires Prescription (YES/NO)

Yes

Generics

Progesterone

Used For

Hormone Replacement Therapy

How it works

Progesterone prepares the endometrium for the potential of pregnancy after ovulation. It triggers the lining to thicken to accept a fertilized egg. It also prohibits the muscle contractions in the uterus that would cause the body to reject an egg.

Dosage

Progesterone

Side Effects

Diziness , headache , fatigue , emotional lability , abdominal pain / distension , musculoskeletal pain, early or rarely delayed menstruation. soreness , diarrhoea , flatulence with rectal route.

Drug Interactions

CYP450-3A4 such as barbiturates, anti-epileptic agents (phenytoin, carbamazepine), rifampicin, phenylbutazone, bromcriptine, spironolactone, griseofulvin, some antibiotics (ampicillins, tetracyclines) and also herbal products containing St. John's wort, (Hypericum perforatum) , Ketokonazole and other inhibitors of CYP450-3A4 such as ritonavir and nelfinavir , ciclosporin , Aminoglutethimide , coumarins , anti-diabetic drugs , diazepam , tizanidine , terbinafine .

Indication

It is used in various female reproductive health conditions associated with low progesterone.

When not to Use

Known hypersensitivity to the active substances, soybean lecithin, peanut or to any of the excipients listed . Known or Past or suspected breast cancer , Known or suspected estrogen-dependent malignant tumours (e.g genital tract carcinoma) , Undiagnosed genital bleeding.

Precaution

Before initiating or reinstituting HRT, a complete personal and family medical history should be taken.

Warning 1

For the treatment of postmenopausal symptoms, HRT should only be initiated for symptoms that adversely affect quality of life. In all cases, a careful appraisal of the risks and benefits should be undertaken at least annually, and HRT should only be continued as long as the benefit outweighs the risk.

Warning 2

HRT is associated with a 1.3-3 fold risk of developing venous thromboembolism (VTE), i.e. deep vein thrombosis or pulmonary embolism.

Warning 3

Women already on chronic anticoagulant treatment require careful consideration of the benefit-risk of use of HRT.

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store in a refrigerator (2°C–8°C). Do not Freeze .