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Specification
Requires Prescription (YES/NO)
Yes
Generics
Nalbuphine HCl
Used For
Pain & Inflammation
How it works
Nalbuphine Hydrochloride is an agonist at kappa (k) opioid receptors and an antagonist at mu (µ) receptors. It is without significant effects on delta opioid receptors. It produces typical opioid effects in the central nervous system, such as analgesia and depression of respiration but may also act as an opioid antagonist.
Usage And Safety
Dosage
Nalbuphine HCl
Side Effects
Dizziness, sweating, dry mouth and headache .
Drug Interactions
CNS depressants.
Indication
Relief of moderate to serve pain : Nalbuphine Hydrochloride is effective in the relief of postoperative pain and in the treatment of pain associated with myocardial infarction .
When not to Use
The only absolute contraindication to the use of Nalbuphine Hydrochloride is known sensitivity to the drug. Caution is required in the following circumstance. 1. Established respiratory depression. 2. Individuals physically dependent on opioid analgesics. 3. Conditions where clouding of consciousness is undesirable. 4. Raised intracranial pressure.
Precautions
Precaution
In common with all drugs having opioid agonist activity Nalbuphine Hydrochloride has respiratory depressant effect and at usual therapeutic doses this is similar to that of morphine. Care is required in patients with impaired respiratory drive.
Warnings
Warning 1
Withdrawal effects may occur following administration of Nalbuphine Hydrochloride to patients who are physically dependent on opioids because of its opioid antagonist action. Its use in such patients should therefore be avoided.
Warning 2
The drug is not recommended for use in neonates.
Warning 3
Breast milk, there is no information on Nalbuphine Hydrochloride and lactation but the use of the drug during lactation should be avoided.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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