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Specification
Requires Prescription (YES/NO)
Yes
Generics
Itopride Hydrochloride
Used For
Dyspepsia
How it works
It (Itopride hydrochloride) activates gastrointestinal propulsive motility due to its dopamine D2 antagonizing activity and acetylcholinesterase inhibitory activity. Itopride activates acetylcholine release and inhibits its degradation.
Usage And Safety
Dosage
Itopride Hydrochloride
Side Effects
Blood and lymphatic system disorders : Leukopenia and thrombocytopenia. Immune system disorders : Anaphylactoid reaction, Endocrine disorders Increased prolactin level and gynecomastia. Nervous system disorders : Dizziness, headache and tremor . Gastrointestinal disorders : Diarrhea, constipation, abdominal pain, increased saliva and nausea. Hepato-biliary disorders Jaundice. Skin and subcutaneous tissue disorders Rash, redness, and itching.
Drug Interactions
Particular caution should be taken with drugs with a narrow therapeutic index, sustained release or enteric-coated formulations. Anti-ulcer drugs like cimetidine, ranitidine, teprenone and cetraxate do not the prokinetic action of itopride, Anticholinergic drugs may reduce the action of itopride.
Indication
Itopride hydrochloride is used in the treatment of gastrointestinal symptoms of functional, nonulcer dyspepsia (chronic gastritis) i.e., sensation of bloating, early satiety, upper abdominal pain or discomfort, anorexia, heartburn, nausea and vomiting.
When not to Use
It (Itopride hydrochloride) is contraindicated in patients with known hypersensitivity to itopride hydrochloride or any of the excipients. It should not be used in patients in whom an increase in gastrointestinal motility could be harmful .
Precautions
Precaution
It (Itopride hydrochloride) enhances the action of acetylcholine and may produce cholinergie side effects.
Warnings
Warning 1
The dose may be reduced according to the patient's age and symptoms.
Warning 2
It should not be used in patients in whom an increase in gastrointestinal motility could be harmful, e.g. gastrointestinal hemorrhage, mechanical obstruction or perforation.
Warning 3
There are no adequate and well-controlled studies in pregnant women. Therefore, Itopride hydrochloride should not be used during pregnancy unless the benefits outweigh the potential risks.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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