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Specification
Requires Prescription (YES/NO)
Yes
Generics
Nepafenac
Used For
Eye Inflammation
How it works
Nepafenac is a non-steroidal anti-inflammatory and analgesic prodrug. After topical ocular dosing, nepafenac penetrates the cornea and is converted by ocular tissue hydrolases to amfenac, a nonsteroidal anti-inflammatory drug. Amfenac inhibits the action of prostaglandin H synthase (cyclooxygenase), an enzyme required for prostaglandin production.
Usage And Safety
Dosage
Nepafenac
Side Effects
Effects in the eye: Iris inflammation, eye pain, eye discomfort, dry eye, eyelid swelling, eye irritation, itchy eye, eye discharge, allergic conjunctivitis (eye allergy), increased tear production, deposits on the eye surface, fluid or swelling at the back of the eye, eye redness. General side effects: Dizziness, headache, allergic symptoms (eyelid allergic swelling), nausea, skin inflammation, redness and itching.
Drug Interactions
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Nepafenac can affect or be affected by other medicines you are using, including other eye drops for the treatment of glaucoma. Also tell your doctor if you are taking medicines that reduce blood clotting (warfarin) or other NSAIDs. They may increase the risk of bleeding.
Indication
It is to be used by adults to prevent and relieve eye pain and inflammation following cataract surgery on the eye and to reduce the risk of macular oedema (swelling in the back of the eye) following cataract surgery on the eye in diabetic patients .
When not to Use
Do not use - If you are allergic to nepafenac or any of the other ingredients of this medicine . - If you are allergic to other nonsteroidal anti-inflammatory drugs (NSAID) - If you have experienced asthma, skin allergy, or intense inflammation in your nose when using other NSAIDs. Examples of NSAIDs are: acetylsalicylic acid, ibuprofen, ketoprofen, piroxicam, diclofenac .
Precautions
Precaution
Use of topical NSAIDs may result in keratitis. In some susceptible patients, continued use of topical NSAIDs may result in epithelial breakdown, corneal thinning, corneal erosion, corneal ulceration or corneal perforation . These events may be sight threatening. Patients with evidence of corneal epithelial breakdown should immediately discontinue use of nepafenac and should be monitored closely for corneal health.
Warnings
Warning 1
An acute ocular infection may be masked by the topical use of anti-inflammatory medicines. NSAIDs do not have any antimicrobial properties. In case of ocular infection, their use with anti-infectives should be undertaken with care.
Warning 2
Wearing contact lens is not recommended during the postoperative period following cataract surgery. Therefore, patients should be advised not to wear contact lenses unless clearly indicated by their doctor.
Warning 3
The product should not be injected. Patients should be instructed not to swallow nepafenac .
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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