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Specification
Requires Prescription (YES/NO)
Yes
Generics
Mupirocin
Used For
Bacterial Infection
How it works
Mupirocin is a novel antibiotic produced through fermentation by Pseudomonas fluorescens. Mupirocin inhibits isoleucyl transfer-RNA synthetase, thereby arresting bacterial protein synthesis. Mupirocin has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally.
Usage And Safety
Dosage
Mupirocin
Side Effects
Common (approximately 2%): itching, burning, erythema, stinging, pain/swelling at site of application and dryness. Less than 1% of patients discontinued therapy because of these local reactions. Uncommon: Cutaneous sensitisation reactions to mupirocin or the ointment base.
Drug Interactions
It should not be combined with other topical preparations as there is a risk of dilution, resulting in a reduction in the antibacterial activity and potential loss of stability of the mupirocin.
Indication
It is indicated for the topical treatment of mild impetigo.
When not to Use
It is contraindicated in patients who have demonstrated hypersensitivity to mupirocin calcium or any components of the formulations.
Precautions
Precaution
If a reaction suggesting sensitivity or chemical irritation should occur with the use of mupirocin , treatment should be discontinued, the product should be wiped off and appropriate alternative therapy for the infection instituted.
Warnings
Warning 1
It is not suitable for ophthalmic use, intranasal use or application to other mucosal surfaces .
Warning 2
Avoid contact with eyes. If contaminated, the eyes should be thoroughly irrigated with water until the residues have been removed.
Warning 3
As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. Appropriate measures should be taken if this occurs.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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