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Specification
Requires Prescription (YES/NO)
Yes
Generics
Cefixime
Used For
Bacterial Infection
How it works
Like other cephalosporins, cefixime exhibits its bactericidal action by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis.
Usage And Safety
Dosage
Cefixime
Side Effects
Diarrhea (if severe diarrhea occurs, cefixime should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, Headache, dizziness, seizures , Transient rises in liver transaminases,alkaline phosphatase and jaundice , elevation of serum amylase.
Drug Interactions
Anticoagulants , Carbamazepine , probenecid.
Indication
Cefixime is indicated in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: - Uncomplicated urinary tract infections - Otitis media - Pharyngitis and tonsillitis - Acute bronchitis and acute exacerbations of chronic bronchitis - Uncomplicated gonorrhea (cervical/urethral).
When not to Use
Cefixime is contraindicated in: Patients with hypersensitivity to any component of this medication. Patients with known allergy to the cephalosporin group of antibiotics.
Precautions
Precaution
Cephalosporins should be given with caution to penicillinsensitive patients, as there is some evidence of partial cross-allergenicity between the penicillins and cephalosporins.
Warnings
Warning 1
Cefixime should be administered with caution in patients with markedly impaired renal function.
Warning 2
Treatment with broad spectrum antibiotics alters the normal flora of the colon and may permit overgrowth of clostridia.
Warning 3
Broad-spectrum antibiotics such as cefixime should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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