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Specification
Requires Prescription (YES/NO)
Yes
Generics
Dexamethasone
Used For
Eye Inflammation
How it works
Dexamethasone is a highly potent and long-acting glucocorticoid. It has an approximately 7 times greater anti-inflammatory potency than prednisolone, another commonly prescribed corticosteroid. Corticosteroids will inhibit phospholipase A2 thereby preventing the generation of substances which mediate inflammation, for example, prostaglandins. Corticosteroids also produce a marked, though transient, lymphocytopenia. This depletion is due to redistribution of the cells, the T lymphocytes being affected to a greater degree than the B lymphocytes. Lymphokine production is reduced, as is the sensitivity of macrophages to activation by lymphokines. Corticosteroids also retard epithelial regeneration, diminish post-inflammatory neo-vascularisation and reduce towards normal levels the excessive permeability of inflamed capillaries.
Usage And Safety
Dosage
Dexamethasone
Side Effects
Common (may affect up to 1 in 10 people): • discomfort, irritation, burning, stinging, itching and blurred vision after use. These are usually mild and do not last long. Uncommon (may affect up to 1 in 100 people): • allergic reactions • prolonged healing of wounds • cataract (clouding of the lens inside the eye) • infections • glaucoma (caused by high pressure in the eye). Very rare (may affect up to 1 in 10,000 people): • conjunctivitis (inflammation of the surface of the eye, causing redness , watering and irritation • increase in the size of the pupil • swelling of the face • drooping eyelids • inflammation inside the eye which causes pain and redness (uveitis), • formation of calcium crystals on the surface of the eye • changes in the thickness of the surface of the eye, • ulcer on the surface of the eye causing pain, watering, redness, and vision loss, • perforation of the surface of the eye (the cornea), • swelling of the surface of the eye (corneal oedema), • inflamed surface of the eye giving blurred vision, dry eyes, sensitivity to light, burning, tears and a sandy sensation in your eye (crystalline keratopathy).
Drug Interactions
• Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. • Some medicines may increase the effects of Dexamethasone Phosphate Eye Drops and your doctor may wish to monitor you carefully if you are taking these medicines (including some medicines for HIV: ritonavir, cobicistat).
Indication
Dexamethasone Eye Drops is used to treat inflammation of your eyes.
When not to Use
Do not use Dexamethasone Eye Drops • if you are suffering from an eye infection that you are not using a medicine for • if you have damage to the surface of the eye (including ulcers or injuries which have not healed properly), unless otherwise recommended by your ophthalmologist • if you have high pressure in the eye known to be caused by steroids unless otherwise recommended by your ophthalmologist • if you are allergic (hypersensitive) to dexamethasone phosphate, or any of the other ingredients of this medicine .
Precautions
Precaution
Care should be taken to ensure that the eye is not infected before Dexamethasone Eye Drops, solution is used.
Warnings
Warning 1
If you have severe allergic conjunctivitis (redness, swelling, itching and tears in the eye) that another medicine has not been able to treat, only use Dexamethasone Eye Drops for a short period of time.
Warning 2
If you are diabetic, tell your ophthalmologist or optician that you are using Dexamethasone Eye Drops.
Warning 3
If you usually wear contact lenses: avoid wearing contact lenses while you are using Dexamethasone Eye Drops.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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