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Specification
Requires Prescription (YES/NO)
Yes
Generics
Human Chorionic Gonadotropin
Used For
Female Infetility , Male Infertility
How it works
The action of hCG is virtually identical to that of pituitary although hCG also seems to have a small degree of FSH activity. In male, it is given in an attempt to stimulate the interstitial cells of the testes (cells of Leydig) to produce androgen and in female, in the second phase of the cycle, to maintain the functional integrity of the corpus luteum and to stimulate its secretion of progesterone.
Usage And Safety
Dosage
Human Chorionic Gonadotropin
Side Effects
Shock: Because shock may occur in rare cases, sufficient monitoring should be made. In case facial blush, heartburn, dyspnea, etc. occur, the administration should be discontinued and proper treatments made.Hypersensitivity: Since rash and so on may occur, the administration should be discontinued in case of this.Psychoneural System: Dizziness, excitation, insomnia, depression, fatigue, etc. may occur.Circulatory System: Thrombosis and cerebral thrombosis can rarely occur.Continuous administration for a long time: Hypersexuality, sustained penis erection, acne, and gynecomastia can occur in male and signs of masculinization such as trachyphonia, polytrichia, clitorism, acne, etc. in female. Others: In case signs of precocious puberty occur during the administration to prepubertal patients, administration should be discontinued
Drug Interactions
In case hCG is administered after or in combination with follicle stimulating hormone to induce ovulation, ovarian hyperstimulation syndrome such as Meigs syndrome accompanied by ovarian swelling, rupture of tumid ovary, ascites and pleural effusion may occur and furthermore thrombosis and cerebral infarction can be caused by hemeconcentration and an accentuation of blood coagulation capability.
Indication
It is used to treat : Hypogonadotropic Disorders like Cryptorchidism, Hypogonadism, Hypogonadotropic eunuchoidism, Sperm asthenia Azoospermia, Hypomenorrhea (Extended follicular phase), Hypermenorrhea or Metropathia hemorrhagica, Threatened abortion, Habitual abortion, Primary and secondary amenorrhea or Anovulatory cycle.
When not to Use
Patients with prostatic carcinoma or other androgen-dependent neoplasm and who are suspicious to have such diseases. Patients with a prior allergic reaction to gonadotropins. - Patients with precocious puberty.
Precautions
Precaution
Since there is a risk of multiple birth, patients should be informed of this previously.
Warnings
Warning 1
Whether patients have subjective symptoms such as abdominal pain, abdominal discomfort, vomiting, lumbago, etc. should be cautiously monitored.
Warning 2
Whether patients have ovarian swelling should be confirmed by an internal examination.
Warning 3
Pain at site of injection can be caused by intramuscular injection.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store in a refrigerator (2°C–8°C). Do not Freeze .
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