Gavel 60ml Suspension 250mg/5ml

Requires Prescription (YES/NO)

Yes

Generics

Ciprofloxacin HCl

Used For

Bacterial Infection

How it works

It acts via inhibition of bacterial DNA gyrase (topoisomerase, which is essential in the reproduction of bacterial DNA), ultimately resulting in interference with DNA function. Ciprofloxacin is highly active against a wide range of Gram-positive and Gram-negative organisms and has shown activity against some anaerobes.

Dosage

Ciprofloxacin HCl

Side Effects

Nausea, Diarrhoea , Mycotic superinfections, Eosinophilia, Anorexia, Psychomotor hyperactivity / agitation, Headache, Dizziness, Sleep disorders, Taste disorders, Vomiting, Gastrointestinal and abdominal pains, Dyspepsia, Flatulence, Increase in transaminases, Increased bilirubin, Rash, Pruritus, Urticaria, Musculoskeletal pain (e.g. extremity pain, back pain, chest pain), Arthralgia, Renal impairment, Asthenia, Fever, Increase in blood alkaline phosphatase.

Drug Interactions

Theophylline, clozapine, tacrine, ropinirole, tizanidine, duloxetine , Chelation complex formulation like , calcium, magnesium, aluminum or iron), polymeric phosphate binders (e.g., sevelamer), sucralfate or antacids and highly buffered drugs (e.g., didanosine ) , caffeine or pentoxifylline (oxpentifylline) , Phenytoin , Glyburide/Glibenclimide , Warfarin , Probencid , Methotrexate , Metoclopramide , Omeprazole , Cyclosporin , Sildenafil.

Indication

It is used to treat : • Lower respiratory tract infections due to Gram-negative bacteria• Acute exacerbation of chronic sinusitis especially if these are caused by Gram-negative bacteria• Urinary tract infections• Genital tract infections

When not to Use

Ciprofloxacin is contraindicated in patients with a history of hypersensitivity to ciprofloxacin, any member of the quinolone class of antimicrobial agents or any of the product components. - Concomitant administration with tizanidine is contraindicated.

Precaution

Cases of hepatic necrosis and life-threatening hepatic failure have been reported with ciprofloxacin. In the event of any signs and symptoms of hepatic disease (such as anorexia, jaundice, dark urine, pruritus, or tender abdomen), treatment should be discontinued.

Warning 1

Hypersensitivity and allergic reactions, including anaphylaxis and anaphylactoid reactions, may occur following a single dose and may be life-threatening.If such reaction occurs, ciprofloxacin should be discontinued and an adequate medical treatment is required.

Warning 2

Ciprofloxacin should be discontinued in patients experiencing symptoms of neuropathy, including pain, burning, tingling, numbness, and/or weakness in order to prevent the development of an irreversible condition.

Warning 3

Patients with a family history of actual defects in glucose-6-phosphate dehydrogenase activity are prone to hemolytic reactions with quinolones, and so ciprofloxacin should be used with caution in these patients.

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.