Exempa-Lin Met XR 25mg/5mg/1000mg Tablets ( 1 Strip =7 Tablets )

( 1 Box =14 Tablets )

Active Ingredients and Their Functions:

1. Empagliflozin:
   • Class: Sodium-glucose co-transporter 2 (SGLT2) inhibitor.
   • Function: Lowers blood sugar levels by promoting the excretion of excess glucose through the urine.
2. Linagliptin:
   • Class: Dipeptidyl peptidase-4 (DPP-4) inhibitor.
   • Function: Enhances the body’s natural ability to regulate blood sugar by increasing insulin production and decreasing glucose production in the liver.
3. Metformin (1000 mg):
   • Class: Biguanide.
   • Function: Decreases hepatic glucose production, improves insulin sensitivity, and increases peripheral glucose uptake.

Key Benefits:

• Triple Mechanism of Action: Addresses high blood sugar through multiple pathways for better control.
• Improved Glycemic Control: Helps in reducing HbA1c levels and maintaining them within the target range.
• Convenient Dosage Form: Simplifies treatment regimens by combining three medications into one tablet.

Indications:

• For adults with Type 2 Diabetes Mellitus who require multiple anti-diabetic agents to achieve optimal blood sugar control.
• Especially beneficial for patients inadequately controlled on metformin alone or those already being treated with empagliflozin, linagliptin, and metformin as separate tablets.

Dosage and Administration:

• Dosage: As prescribed by a healthcare professional. The dosage may vary based on individual health conditions and blood sugar levels.
• Administration: Take orally once daily with meals to reduce gastrointestinal side effects associated with metformin.
• Swallow Whole: Do not crush, chew, or break the tablet.

Precautions:

• Renal Function: Regular monitoring is advised as metformin is contraindicated in patients with severe renal impairment.
• Hydration: Maintain adequate fluid intake to prevent dehydration and kidney issues.
• Hypoglycemia Risk: Be cautious when used with insulin or insulin secretagogues.
• Lactic Acidosis: Watch for symptoms like muscle pain, breathing difficulties, and fatigue.

Possible Side Effects:

• Common: Urinary tract infections, genital infections, diarrhoea, nausea, and hypoglycemia.
• Serious: Lactic acidosis, pancreatitis, allergic reactions, and dehydration.

Contraindications:

• Hypersensitivity to empagliflozin, linagliptin, metformin, or any other component of the tablet.
• Patients with Type 1 Diabetes or diabetic keto-acidosis.
• Severe renal impairment or liver dysfunction.

Storage:

• Store in a cool, dry place below 25°C (77°F).
• Keep out of reach of children.

Consultation Advice:

• Always consult your healthcare provider before starting or changing the dosage.
• Inform your doctor about any other medications you are taking to avoid potential interactions.
• Not recommended for use during pregnancy or breastfeeding unless advised by a doctor.