Erythrocin 60ml Suspension 200mg/5ml

Requires Prescription (YES/NO)

Yes

Generics

Erythromycin stearate

Used For

Bacterial Infection

How it works

Erythromycin exerts its antimicrobial action by binding to the 50S ribosomal sub-unit of susceptible microorganisms and suppresses protein synthesis. Erythromycin is usually active against most strains of the following organisms both in vitro and in clinical infections: Gram positive bacteria - Listeria monocytogenes, Corynebacterium diphtheriae (as an adjunct to antitoxin), Staphylococci spp, Streptococci spp (including Enterococci). Gram negative bacteria - Haemophilus influenzae, Neisseria meningitidis, Neisseria gonorrhoeae, Legionella pneumophila, Moraxella (Branhamella) catarrhalis, Bordetella pertussis, Campylobacter spp. Mycoplasma - Mycoplasma pneumoniae, Ureaplasma urealyticum. Other organisms - Treponema pallidum, Chlamydia spp, Clostridia spp, L-forms, the agents causing trachoma and lymphogranuloma venereum

Dosage

Erythromycin stearate

Side Effects

GI upset , Cholestatic jaundice , allergic reactions , reversible hearing loss , pancreatitis , cardiac effects , Myssthaenia like syndrome , Stevens-Johnson syndrome , toxic epidermal necrolysis , hepatotoxicity , hypotension , interstitial nephritis , hallucinations , chest pain , fever , malaise , QT Prolongation.

Drug Interactions

Astemizole, terfenadine or mizolastine , domperidone pimozide ergotamine or dihydroergotamine cisapride , statins protease inhibitors , oral contraceptives. , colchicine , cimetidine and omeprazole , clarithromycin, rifabutin, or rifampicin , fluconazole, ketoconazole and itraconazole , digoxin, quinidine or disopyramide , cilostazol , hexobarbitone, phenobarbital or midazolam , Anticoagulants e.g. warfarin, acenocoumarol and rivaroxaban, valproate, carbamazepine or phenytoin, theophylline ciclosporin or tacrolimus , bromocriptine zopiclone or triazolam/alprazolam , alfentanil (a medicine used to provide pain relief) , methylprednisolone , St John’s Wort (a herbal medicine used to treat depression) , verapamil (used to treat high blood pressure and chest pain) , vinblastine .

Indication

It is used to prevent and treat infections such as: • Throat and sinus infections • Chest infections, such as bronchitis and pneumonia • Ear infections • Mouth and dental infections • Eye infections • Skin and tissue infections, such as acne • Stomach and intestinal infections .

When not to Use

You should not receive if you: • Have been told that you are allergic to erythromycin or other macrolide antibiotics such as clarithromycin or azithromycin or any of the other ingredients .

Precaution

Erythromycin is excreted principally by the liver, so caution should be exercised in administering the antibiotic to patients with impaired hepatic function or concomitantly receiving potentially hepatotoxic agents. Hepatic dysfunction including increased liver enzymes and/or cholestatic hepatitis, with or without jaundice, has been infrequently reported with erythromycin.

Warning 1

As with other macrolides, rare serious allergic reactions, including acute generalised exanthematous pustulosis (AGEP) have been reported. If an allergic reaction occurs, the drug should be discontinued and appropriate therapy should be instituted. Physicians should be aware that reappearance of the allergic symptoms may occur when symptomatic therapy is discontinued.

Warning 2

Rhabdomyolysis with or without renal impairment has been reported in seriously ill patients receiving erythromycin concomitantly with statins.

Warning 3

There have been reports suggesting erythromycin does not reach the foetus in adequate concentrations to prevent congenital syphilis. Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen.

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.