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Specification
Requires Prescription (YES/NO)
Yes
Generics
Ertugliflozin
Used For
Diabetes
How it works
Ertugliflozin : Ertugliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, Ertugliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion. Ertugliflozin also causes an osmotic diuresis, which may result in increase of urinary glucose excretion.
Usage And Safety
Dosage
Ertugliflozin
Side Effects
Pancreatitis, hypotension, ketoacidosis, acute kidney injury, impairment in renal function, urosepsis, pyelonephritis, lower limb amputation, heart failure, hypoglycemia with concomitant use with insulin and insulin secretagogues, necrotizing fasciitis of the perineum (fournier’s gangrene), genital mycotic infections, hypersensitivity reactions, increases in low-density lipoprotein, severe and disabling arthralgia, bullous pemphigoid, upper respiratory tract infection, nasopharyngitis, urinary tract infections, vaginal pruritus, increased urination, back pain, weight decreased and headache.
Drug Interactions
It may increase the risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue.Patients receiving digoxin should be monitored appropriately .
Indication
It is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both Ertugliflozin and Sitagliptin is appropriate.
When not to Use
Known hypersensitivity to Ertugliflozin, Sitagliptin and to any of the excipient of the product. - Severe renal impairment, end-stage renal disease (ESRD) or on dialysis.
Precautions
Precaution
Patients should be observed carefully for signs and symptoms of pancreatitis.
Warnings
Warning 1
Ertugliflozin causes intravascular volume contraction.
Warning 2
Treatment with medicines containing SGLT2 inhibitors increases the risk for urinary tract infections. Evaluate patients for signs and symptoms of urinary tract infections and treat promptly, if indicated.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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