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Yes
Carbamazepine
Epilepsy
Carbamazepine is a sodium channel blocker. It binds preferentially to voltage-gated sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.
Carbamazepine
Up to 1 in 10 people have experienced: Changes in the blood including an increased tendency to bruise or bleed; fluid retention and swelling; weight increase; low sodium in the blood which might result in confusion; headache; double or blurred vision; dry mouth. Up to 1 in 100 people have reported: Abnormal involuntary movements including tremor or tics; abnormal eye movements; diarrhoea; constipation. Up to 1 in 1,000 people have reported: Disease of the lymph glands; folic acid deficiency; a generalised allergic reaction including rash, joint pain, fever, problems with the kidneys and other organs; hallucinations; depression; loss of appetite; restlessness; aggression; agitation; confusion; speech disorders; numbness or tingling in the hands and feet; muscle weakness; high blood pressure (which may make you feel dizzy, with a flushed face, headache, fatigue and nervousness); low blood pressure (the symptoms of which are feeling faint, light headed, dizzy, confused, having blurred vision); changes to heart beat; stomach pain; liver problems including jaundice; symptoms of lupus.
Hormone contraceptives , Hormone Replacement Therapy (HRT) , Any medicines for depression or anxiety. , Corticosteroids (‘steroids’) , Anticoagulants , ciprofloxacillin , Antifungals to treat fungal infections , Painkillers containing paracetamol, dextropropoxyphene, tramadol, methadone or buprenorphine ,Other medicines to treat epilepsy , Medicines for high blood pressure or heart problems , Antihistamines (medicines to treat allergy such as hayfever, itch, etc) , Diuretics (water tablets) , Cimetidine or omeprazole (medicines to treat gastric ulcers) , Isotretinoin (a medicine for the treatment of acne) , Metoclopramide or aprepitant (anti-sickness medications) , Acetazolamide (a medicine to treat glaucoma - increased pressure in the eye) , Danazol or gestrinone (treatments for endometriosis) , Theophylline or aminophylline (used in the treatment of asthma) , Ciclosporin, tacrolimus or sirolimus (immunosuppressants used after transplant operations, but also sometimes in the treatment of arthritis or psoriasis) , Drugs to treat schizophrenia (e.g. paliperidone, aripiprazole) , Cancer drugs (e.g. temsirolimus, cyclophasphamide, lapatinib) , The anti-malarial drug, mefloquine , Drugs to treat HIV , Levothyroxine (used to treat hypothyroidism) , Tadalafil (used to treat impotence) , Albendazole (used to treat worms) , Bupropion (used to help stop smoking) , A herbal remedy called St John’s Wort or Hypericum , Drugs or supplements containing Vitamin B (nicotinamide).
It is used to treat :• To treat some forms of epilepsy• To treat a painful condition of the face called trigeminal neuralgia• To help control serious mood disorders when some other medicines don’t work .
Some people MUST NOT take carbamazepine . Talk to your doctor if:• You think you may be hypersensitive (allergic) to carbamazepine or similar drugs such as oxcarbazepine (Trileptal), or to any of a related group of drugs known as tricyclic antidepressants (such as amitriptyline or imipramine). If you are allergic to carbamazepine there is a one in four (25%) chance that you could also have an allergic reaction to oxcarbazepine.• You think you may be allergic to any of the other ingredients of Tegretol Tablets . Signs of a hypersensitivity reaction include swelling of the face or mouth (angioedema), breathing problems, runny nose, skin rash, blistering or peeling.• you have ever had problems with your bone marrow• you have a blood disorder called porphyria• you have taken drugs called monoamine oxidase inhibitors (MAOIs), used to treat depression, within the last 14 days.
A small number of people being treated with anti-epileptics such as carbamazepine have had thoughts of harming or killing themselves. If at any time you have these thoughts, immediately contact your doctor.
Eating grapefruit, or drinking grapefruit juice, may increase your chance of experiencing side effects.
Your doctor may want you to have a number of blood tests before you start taking carbamazepine and from time to time during your treatment. This is quite usual and nothing to worry about.
It can make you feel dizzy or drowsy, or may cause blurred vision, double vision, or you may have a lack of muscular coordination, especially at the start of treatment or when the dose is changed. If you are affected in this way, or if your eyesight is affected, you should not drive or operate machinery.
Always consult your physician before using any medicine.
Store this medicine at room temperature, away from direct light and heat.
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