Dalacin C Capsules 300Mg (1 Strip = 4 Capsules)

Requires Prescription (YES/NO)

Yes

Generics

Clindamycin HCl

Used For

Bacterial Infection

How it works

Clindamycin is a lincosamide antibiotic with a primarily bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria. Lincosamides such as clindamycin bind to the 50S subunit of the bacterial ribosome similarly to macrolides such as erythromycin and inhibit protein synthesis. The action of clindamycin is predominantly bacteriostatic although high concentrations may be slowly bactericidal against sensitive strains. Although clindamycin phosphate is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin .

Dosage

Clindamycin HCl

Side Effects

Common: may affect up to 1 in 10 people: Abnormal liver function tests (poor liver function) , pain in the stomach / abdomen, diarrhoea . Uncommon: May affect up to 1 in 100 people : Feeling sick or being sick (throwing up) , rash characterized by a flat red area on the skin that is covered with small bumps, hives . Not known: Frequency cannot be estimated from the available data: Infection inside and around the vagina , inflammation of the large intestine which causes abdominal pain, fever or diarrhoea due to infection by Clostridium difficile. A more severe decrease in a specific class of white blood cell (agranulocytosis), a reduction in the number of white blood cells (leucopenia), a decrease in the number of white blood cells (neutropenia), a reduced number of platelets in the blood (thrombocytopenia), an increase in the number of white blood cells (eosinophilia) , changes in the way things taste , inflammation of the lining of the oesophagus (gullet), open sores or lesions in the lining of the oesophagus (gullet) .

Drug Interactions

Keratolytics , neuromuscular blocking agents , erythromycin , Vit k antagonists.

Indication

It is used to treat serious infections caused by germs (bacteria). - To help prevent serious infections during and after surgery.

When not to Use

Clindamycin hydrochloride is contraindicated in patients with a known hypersensitivity to clindamycin or lincomycin or to any ingredient in the formulation or component of the container.

Precaution

Serious hypersensitivity reactions, including anaphylactoid reactions, severe skin reactions such as drug reaction with eosinophilia and systemic symptoms (DRESS), and dermatological reactions including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) have been reported in patients on clindamycin therapy. If a hypersensitivity reaction occurs clindamycin should be discontinued and appropriate therapy should be initiated.

Warning 1

In patients with G-6-PD deficiency, the combination of clindamycin with primaquine may cause hemolytic reactions. Routine blood examinations should be done during therapy with primaquine to monitor potential hematologic toxicities.

Warning 2

Clindamycin hydrochloride should be prescribed with caution in atopic individuals.

Warning 3

It should be prescribed with caution in patients with a history of gastrointestinal disease, particularly colitis, inflammatory bowel disease (including regional enteritis and ulcerative colitis), or a history of antibiotic-associated colitis (including pseudomembranous colitis).

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.