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Yes
Cyproterone Acetate + Ethinyl Estradiol
Acne
The substance cyproterone acetate contained in this medicine blocks the effect of endogenously produced and exogenously administered androgens at the target organs by means of competitive inhibition. The stimulating effect of male sex hormones on androgen-dependent structures and functions is weakened or abolished by cyproterone acetate. Excessive sebaceous gland function is decreased. Apart from the described anti-androgen effect, cyproterone acetate also has a progestational action. The ethinylestradiol in the combination inhibits ovulation and changes the cervical mucus and the endometrium rendering them unfavourable for sperm penetration and nidation of a fertilised ovum, respectively.
Cyproterone Acetate + Ethinyl Estradiol
Common side effects (may affect up to 1 in 10 people) : Feeling sick , stomach ache , putting on weight , headaches , depressive moods or mood swings , sore or painful breasts . Uncommon side effects (may affect up to 1 in 100 people) being sick and stomach upsets , fluid retention , migraine , loss of interest in sex , breast enlargement , skin rash, which may be itchy . Rare side effects (may affect up to 1 in 1,000 people) : Poor tolerance of contact lenses , losing weight .
Anti-epileptic agents, antibiotics, barbiturates and rifampicin , primidone, phenytoin, carbamazepine, oxcarbazepine , ritonavir, nevirapine, efavirenz , griseofulvin, ketoconazole , etoricoxib , theophylline , tizanidine
It is used to treat skin conditions such as acne, very oily skin and excessive hair growth in women of reproductive age.
• Preparations containing oestrogen/progestogen combinations should not be used in the presence of any of the conditions listed below. Should any of the conditions appear for the first time during their use, the product should be stopped immediately.• Concomitant use with another hormonal contraceptive • Venous thrombosis present or in history (deep venous thrombosis, pulmonary embolism) • Arterial thrombosis present or in history (e.g. myocardial infarction) or prodromal conditions (e.g. angina pectoris and transient ischaemic attack). • Presence or history of cerebrovascular accident
Surgery is more likely to be associated with an increased incidence of thrombotic side-effects. Adequate precaution should be taken. Under no circumstances should the oral contraceptive tablet be stopped without having adopted a satisfactory alternative method of contraception.
It is not for use in men and should not be used in children.
Hypertension may occur in association with the use of oral contraceptives. Regular blood-pressure checks, including a pretreatment level, are advisable.
Prolonged amenorrhoea following the use of oral contraceptives may occur. Caution is advised where oligomenorrhoea or amenorrhoea have occurred in the past.
Always consult your physician before using any medicine.
Store this medicine at room temperature, away from direct light and heat
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