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Specification
Requires Prescription (YES/NO)
Yes
Generics
Perindopril
Used For
Hypertension
How it works
It is an angiotensin converting enzyme (ACE) inhibitor. These work by widening the blood vessels, which makes it easier for your heart to pump blood through them.
Usage And Safety
Dosage
Perindopril
Side Effects
Common (occur in fewer than 1 in 10 users but in more than 1 in 100 users): headache, dizziness, vertigo, pins and needles, vision disturbances, tinnitus (sensation of noises in the ears), lightheadedness due to low blood pressure, cough, shortness of breath, gastro-intestinal disorders (nausea, vomiting, abdominal pain, taste disturbances, dyspepsia or difficulty of digestion, diarrhoea, constipation), allergic reactions (such as skin rashes, itching), muscle cramps, feeling of tiredness, Uncommon (occur in fewer than 1 in 100 users but in more than 1 in 1000 users): mood swings, sleep disturbances, bronchospasm (tightening of the chest, wheezing and shortness of breath), dry mouth, angioedema (symptoms such as wheezing, swelling of the face, tongue or throat, intense itching or severe skin rashes), kidney problems, impotence, sweating.
Drug Interactions
• Other medicines for high blood pressure, including diuretics (medicines which increase the amount of urine produced by the kidneys), • Potassium-sparing diuretics (spironolactone, triamterene, amiloride), potassium supplements or potassium-containing salt substitutes, • Lithium for mania or depression, • Non-steroidal anti-inflammatory drugs (e.g. ibuprofen) for pain relief or high dose aspirin, • Medicines to treat diabetes (such as insulin or metformin), • Medicines to treat mental disorders such as depression, anxiety, schizophrenia etc (e.g. tricyclic antidepressants, antipsychotics), • Immunosuppressants (medicines which reduce the defence mechanism of the body) used for the treatment of auto-immune disorders or following transplant surgery (e.g. ciclosporin), • Allopurinol (for the treatment of gout), • Procainamide (for the treatment of an irregular heart beat), • Vasodilators including nitrates (products that make the blood vessels become wider), • Heparin (medicines used to thin blood), • Medicines used for the treatment of low blood pressure, shock or asthma (e.g. ephedrine, noradrenaline or adrenaline) .
Indication
It is used in : • To treat high blood pressure (hypertension), • To treat heart failure (a condition where the heart is unable to pump enough blood to meet the body’s needs), • To reduce the risk of cardiac events, such as heart attack, in patients with stable coronary artery disease (a condition where the blood supply to the heart is reduced or blocked) and who have already had a heart attack and/or an operation to improve the blood supply to the heart by widening the vessels that supply it.
When not to Use
Do not take • If you are allergic (hypersensitive) to perindopril, to any other ACE inhibitor or to any of the other ingredients in the list. • If you are more than 3 months pregnant. • If you have experienced symptoms such as wheezing, swelling of the face, tongue or throat, intense itching or severe skin rashes with previous ACE inhibitor treatment or if you or a member of your family have had these symptoms in any other circumstances (a condition called angioedema).
Precautions
Precaution
It contains lactose monohydrate. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product .
Warnings
Warning 1
Talk to your doctor before taking If you have aortic stenosis (narrowing of the main blood vessel leading from the heart) or hypertrophic cardiomyopathy (heart muscle disease) or renal artery stenosis (narrowing of the artery supplying the kidney with blood) .
Warning 2
It is not recommended for use in children and adolescents.
Warning 3
Talk to your doctor before taking if you suffer from a collagen vascular disease (disease of the connective tissue) such as systemic lupus erythematosus or scleroderma .
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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