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Specification
Requires Prescription (YES/NO)
Yes
Generics
Disodium Hydrogen Citrate
Used For
Urinary Tract Infection
How it works
Disodium hydrogen citrate, also known as sodium acid citrate, is a urinary alkalinizer. It renders the urine less acidic and promotes a mild diuresis.
Usage And Safety
Dosage
Disodium Hydrogen Citrate
Side Effects
Hypocalcemia , Hypokalemia and metabolic alkalosis symptoms include mood changes, tiredness, shortness of breath, muscle weakness, and irregular heartbeat , Excessive doses of sodium salts may also lead to sodium overload and hyperosmolarity. Large doses of oral citrate salts may result in gastrointestinal events such as diarrhoea, nausea and vomiting, and a laxative effect.
Drug Interactions
Aluminium antacids , chlorpropamide, lithium, methotrexate, methenamine, salicylates and tetracyclines , mecamylamine, flecainide, quinidine and sympathomimetics.
Indication
To render the urine alkaline in conditions such as pyelitis, cystitis, urethritis, urolithiasis and during treatment of urinary tract infections with antibiotics whose action is enhanced by an alkaline pH5,6 such as sulphonamides and fluroquinolones; or to overcome the tendency to acute or chronic metabolic acidosis in acute infections and dehydration.
When not to Use
It is contraindicated in patients with severe renal impairment and associated oliguria, azotemia or anuria; untreated Addison’s disease; acute dehydration; heat cramps; and severe myocardial damage. In addition, sodium salts are contraindicated in patients on sodium restricted diet.
Precautions
Precaution
Serum electrolytes, particularly serum bicarbonate levels, should be monitored in patients with renal disease.
Warnings
Warning 1
It should be used with caution in patients with edematous sodium retaining states; congestive heart failure; hypertension; pulmonary or peripheral edema or toxemia of pregnancy.
Warning 2
Caution is advised in patients with low urinary output or reduced glomerular filtration rates.
Warning 3
Precaution is also advised while using blood products containing citrate in patients with acute liver failure.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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