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Yes
Levobunolol HCl
Glaucoma
Levobunolol is a non-cardioselective beta-adrenoceptor blocking agent, equipotent at both beta-1 and beta-2 receptors. Levobunolol does not have significant local anaesthetic (membrane-stabilizing) or intrinsic sympathomimetic activity. The primary mechanism of the ocular hypotensive activity of levobunolol hydrochloride is likely to be a decrease in aqueous humour production. There is little effect on pupil size or accommodation.
Levobunolol HCl
• Eye irritation/eye pain • Irritation/redness of the outermost layer of the eye • Inflammation of the eyelids and outermost layer of the eye dry eye • Decreased blinking, inflammation of the iris and inner eye or surface of the eye, trouble with your vision, itching of the eye/eye lids, eye and/or eyelid swelling/puffiness, eye discharge or tearing, foreign body sensation in the eye .
Reserpine , systemic beta-blockers.
It is used to treat glaucoma by lowering the pressure that builds up in the eye .
Do not use : • If you are allergic (hypersensitive) to levobunolol, benzalkonium chloride or other ingredients . • If you have or have had asthma or other lung diseases where you have difficulty breathing, wheezing or a chronic cough • If you have or have had heart problems such as heart weakness or heart beat disorders (unless controlled by a pacemaker) .
Due to their negative effect on conduction time, beta-blockers should only be given with caution to patients with first degree atrioventricular block.
If you have a history of breathing problems or heart disease your doctor may monitor you more closely as in rare cases death has been reported following taking levobunolol.
Regular eye examination is required during prolonged and repeated use as the preservative benzalkonium chloride can cause damage to your eyes.
Ophthalmic ß-blockers may induce dryness of eyes. Patients with corneal diseases should be treated with caution.
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