Atconate Tablets 150Mg (1 Box = 1 Tablet)

Requires Prescription (YES/NO)

Yes

Generics

Risedronate Sodium

Used For

Osteoporosis

How it works

It has an affinity for hydroxyapatite crystals in bone and acts as an antiresorptive agent. At the cellular level, it inhibits osteoclasts. The osteoclasts adhere normally to the bone surface, but show evidence of reduced active resorption (e.g., lack of ruffled border). Histomorphometry in rats, dogs, and minipigs showed that its treatment reduces bone turnover (activation frequency, i.e., the rate at which bone remodeling sites are activated) and bone resorption at remodeling sites.

Dosage

Risedronate Sodium

Side Effects

Common: may affect up to 1 in 10 people : • Indigestion, feeling sick, stomach ache, stomach cramps or discomfort, constipation, feelings of fullness, bloating, diarrhoea. • Pain in your bones, muscles or joints.• Headache.Uncommon: may affect up to 1 in 100 people : • Inflammation or ulcer of the oesophagus (the tube that connects your mouth with your stomach) causing difficulty and pain in swallowing , inflammation of the stomach and duodenum (bowel draining the stomach). • Inflammation of the coloured part of the eye (iris) (red painful eyes with a possible change in vision).Rare: may affect up to 1 in 1,000 people : • Inflammation of the tongue (red swollen, possibly painful), narrowing of the oesophagus (the tube that connects your mouth with your stomach). • Abnormal liver tests have been reported. These can only be diagnosed from a blood test.

Drug Interactions

Calcium , magnesium , aluminium (for example some indigestion mixtures) , iron.

Indication

Used in the treatment of osteoporosis : • In postmenopausal women, even if osteoporosis is severe. It reduces the risk of spinal and hip fractures. • In men.

When not to Use

Do not take Risedronate : • If you are allergic to risedronate sodium or any of the other ingredients of this medicine .• If your doctor has told you that you have a condition called hypocalcaemia (a low blood calcium level)• If you may be pregnant, are pregnant or planning to become pregnant• If you are breast-feeding• If you have severe kidney problems.

Precaution

Talk to your doctor or pharmacist before taking Risedronate if you are unable to stay in an upright position (sitting or standing) for at least 30 minutes.

Warning 1

Talk to your doctor or pharmacist before taking Risedronate if you have abnormal bone and mineral metabolism (for example lack of vitamin D, parathyroid hormone abnormalities, both leading to a low blood calcium level).

Warning 2

Talk to your doctor or pharmacist before taking Risedronate if you have had problems in the past with your oesophagus (the tube that connects your mouth with your stomach). For instance you may have had pain or difficulty in swallowing food or you have previously been told that you have Barrett’s oesophagus (a condition associated with changes in the cells that line the lower oesophagus).

Warning 3

Risedronate is not recommended for use in children and adolescents below age 18 due to insufficient data on safety and efficacy.

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.