AMPER Tablets 10Mg/4Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)

Requires Prescription (YES/NO)

Yes

Generics

Amlodipine , Perindopril

Used For

Hypertension

How it works

It is a combination of two active ingredients, perindopril and amlodipine. Perindopril is an ACE (angiotensin converting enzyme) inhibitor. Amlodipine is a calcium antagonist (which belongs to a class of medicines called dihydropyridines). Together they work to widen and relax the blood vessels so that blood passes through them more easily and makes it easier for your heart to maintain a good blood flow.

Dosage

Amlodipine , Perindopril

Side Effects

Very common side effects (may affect more than 1 in 10 people): Edema (Fluid retention). - Common side effects (may affect up to 1 in 10 people): Headache, dizziness, sleepiness (especially at the beginning of treatment), vertigo, numbness or tingling sensation in your limbs, vision disturbances (including double vision), tinnitus (sensation of noises in the ears), palpitations (awareness of your heartbeat), flushing, light-headedness due to low blood pressure, cough, shortness of breath, nausea (feeling sick), vomiting (being sick), abdominal pain, taste disturbances, dyspepsia or difficulty of digestion, change of bowel habit, diarrhoea, constipation, allergic reactions (such as skin rashes, itching), muscle cramps, tiredness, weakness, ankle swelling (oedema peripheral).

Drug Interactions

Aliskiren , diuretics , racecadotril , sirolimus, everolimus, temsirolimus , Sacubitril/valsartan , ibuprofen , insulin , tricyclic antidepressants, antipsychotics, imipramine-like antidepressants, neuroleptics , ciclosporine,tacrolimus , trimethoprim and Co-trimoxazole , allopurinol , procainamide , lithium , estramustine , potassium-sparing drugs (triamterene, amiloride), potassium supplements or potassium-containing salt substitutes , prazosin, alfuzosin, doxazosin, tamsulosin, terazosin, ritonavir, indinavir, nelfinavir , rifampicin, erythromycin, clarithromycin

Indication

It is used for treatment of high blood pressure (hypertension) and/or treatment of stable coronary artery disease (a condition where the blood supply to the heart is reduced or blocked).

When not to Use

Do not take : If you are allergic to perindopril or any other ACE inhibitor, or to amlodipine or any other calcium antagonists, or any of the other ingredients of this medicine , - If you are more than 3 months pregnant , -If you have experienced symptoms such as wheezing, swelling of the face or tongue, intense itching or severe skin rashes with previous ACE inhibitor treatment or if you or a member of your family have had these symptoms in any other circumstances (a condition called angioedema) .

Precaution

Grapefruit juice and grapefruit should not be consumed by people who are taking this medicine. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active ingredient amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of this medicine.

Warning 1

Talk to your doctor, pharmacist or nurse before taking if you have hypertrophic cardiomyopathy (cardiac muscle disease) or renal artery stenosis (narrowing of the artery which supplies the kidney with blood).

Warning 2

Talk to your doctor, pharmacist or nurse before taking if you have severe increase in blood pressure (hypertensive crisis).

Warning 3

Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g. potassium) in your blood at regular intervals

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.