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Specification
Requires Prescription (YES/NO)
Yes
Generics
Triprolidine , Dextromethorphan , Pseudoephedrine
Used For
Fever & Cough
How it works
Triprolidine provides symptomatic relief in conditions believed to depend wholly or partially upon the triggered release of histamine. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class with mild central nervous system depressant properties which may cause drowsiness. Pseudoephedrine has a direct and indirect sympathomimetic activity and is an orally effective upper respiratory decongestant. Pseudoephedrine is substantially less potent than ephedrine in producing both tachycardia and elevation of systolic blood pressure and considerably less potent in causing stimulation of the central nervous system. Dextromethorphan has an antitussive action. It controls coughs by depressing the medullary cough centre.
Usage And Safety
Dosage
Triprolidine , Dextromethorphan , Pseudoephedrine
Side Effects
Very Common (may affect more than 1 in 10 people) : Headache . Common (may affect up to 1 in 10 people) : Difficulty sleeping, dizziness, drowsiness or nervousness , Difficulty performing tasks , Blurred vision n, Thickened mucus, dry mouth, upset stomach or nausea. Rare (may affect up to 1 in 1000 people) : Depression or feeling confused , Tremors, shakiness or slurred speech , Low blood pressure.
Drug Interactions
Sedatives , Hypnotics , bupropion , Tricyclic antidepressants , Sympathomimetic drugs , atropine , guanethidine, methyldopa, adrenergic neurone blockers, debrisoquine, bretylium and betanidine , Moclobemide , Cardiac glycosides , Ergot alkaloids ,Oxytocin , haloperidol, thioridazine, perphenazine , amiodarone, propafenone, quinidine and flecainide , terbinafine , Antihistamines
Indication
It is used to help relieve dry coughs and related congestion symptoms.
When not to Use
Do not use this medicine : *If you have ever had a bad reaction to pseudoephedrine, triprolidine, dextromethorphan or any of the other ingredients. * If you suffer from lung disease. * If you have diabetes * If you have a phaeochromocytoma (rare tumour that affects your heart rate and blood pressure) . *If you have an overactive thyroid gland.
Precautions
Precaution
For all patients, prolonged use of this product may lead to drug dependence (addiction), even at therapeutic doses. The risks are increased in individuals with current or past history of substance misuse disorder (including alcohol misuse) or mental health disorder (e.g., major depression).
Warnings
Warning 1
It may cause drowsiness. This product should not be used to sedate a child.
Warning 2
Ischaemic colitis: Some cases of ischaemic colitis have been reported with pseudoephedrine. Pseudoephedrine should be discontinued, and medical advice sought if sudden abdominal pain, rectal bleeding or other symptoms of ischemic colitis develop.
Warning 3
Use of dextromethorphan with alcohol or other CNS depressants may increase the effects on the CNS and cause toxicity in relatively smaller doses.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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